Studies on Sericin

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Mitogenic effect of sericin on mammalian cells

Fetal bovine serum (FBS) or other mammal-derived factors are extensively supplemented as growth factor into culture medium. Since mammal-derived factors arouses the concern about the risk of zoonosis, serumand mammal-free culture is strongly required. We focused on sericin hydrolysates, originating from silkworm, and reported that sericin is effective as growth factor to various cells. But it i...

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Sericin – A Unique Biomaterial

Silk is made up of two types of proteinssilk fibroin and sericin. Silk sericin is the main residue (≈2030%) in raw silk fiber. It is composed of 18 amino acids. Solubility, molecular weight, and gelling properties of sericin depends on the methods of isolation i.e. degumming. Sericin has proved itself as a highly potential biomaterial by wide variety of applications in medicine, pharmaceuticals...

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Effectiveness of inflammatory cytokines induced by sericin compared to sericin in combination with silver sulfadiazine cream on wound healing.

 Silk sericin (SS) has been shown to promote collagen synthesis during wound healing, but it lacks antimicrobial activity. We investigated the effectiveness and the induction of the inflammatory mediators IL-1bβ and TNF-aα by SS, silver sulfadiazine (SSD) cream, and SS in combination with SSD cream on wound healing in rats. The results show that SS at 8% w/w partially inhibits SSD antibacte...

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Sericin Film: Influence of Concentration on its Physical Properties

Silk sericin (SS) is a glue-like protein from silkworm cocoon. With its outstanding moisturization and activation collagen synthesis properties, silk protein is applied for wound healing. Since wound dressing in film preparation can facilitate patients’ convenience and reduce risk of wound contraction, SS and polyvinyl alcohol (PVA) films were prepared with various concentrations of SS. Their p...

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The effects of sericin cream on wound healing in rats.

Sericin has good hydrophilic properties, compatibility, and biodegradation, it can be used as a wound-healing agent. We evaluated the effects of sericin on wound healing and wound size reduction using rats by generating two full-thickness skin wounds on the dorsum. Group 1 animals were treated with Betadine on left-side (control) wounds and, with 8% sericin cream on right-side (treated) wounds....

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ژورنال

عنوان ژورنال: Journal of the agricultural chemical society of Japan

سال: 1951

ISSN: 0002-1407,1883-6844

DOI: 10.1271/nogeikagaku1924.25.411